With the significant increase in health awareness among modern consumers, the food, cosmetics, and pharmaceutical industries are undergoing a profound shift in safety philosophies. This is reflected in the notable rise in the frequency of keywords like "safe," "natural," and "healthy" in consumer evaluations. This trend is particularly prominent in segments like maternal and infant products, organic foods, and cosmetic care.

The recommended preservative functional ingredient is:

BARENATE HP

INCI: 1,2-HEXANEDIOL, PROPYLENE GLYCOL, HYDROXYACETOPHENONE, PENTYLENE GLYCOL

CAS: 6920-22-5, 57-55-6, 99-93-4, 5343-92-0

Technical Specifications

Items	Specification		MIC
Appearance	Colorless or yellowish transparent liquid		Strain	MIC，%
Odour	Slight characteristic odor		Staphylococcus aureus	0.5
Active matter content ，%	≥60		Pseudomonas aeruginosa	0.6
Solubility	Slightly soluble in water, miscible with low carbon alcohol		Escherichia coli	0.5
pH, 10% aqueous solution，20℃	5.0-7.5		Bacillus subtilis	0.4
Viscosity，20℃	20-25		Aspergillus niger	0.5
Density，20℃，g/ml	0.96-1.03		Canidia Albicans	0.4

Corrosion challenge test experiment of 1.0% concentration in different dosage forms

		Facial mask	Essence	Eye cream	Base emulsion	Primer	Baby wipes	Astringent	Facial cleanser
3d	Bacteria	5×103	4×103	4×103	4×103	3×103	3×103	4×103	4×103
	Fungus	3×103	2×103	3×103	2×103	2×103	2×103	2×103	2×103
7d	Bacteria	3×102	2.5×102	2.5×102	2.5×102	2.5×102	2.5×102	1×102	1×102
	Fungus	2×102	1×102	2×102	1.5×102	2×102	2×102	2×102	1.5×102
14d	Bacteria	1×102	1×102	1×102	1×102	1.2×102	45	40	30
	Fungus	35	25	35	25	25	＜10	＜10	＜10
21d	Bacteria	＜10	＜10	＜10	＜10	＜10	＜10	＜10	＜10
	Fungus	＜10	＜10	＜10	＜10	＜10	＜10	＜10	＜10
28d	Bacteria	＜10	＜10	＜10	＜10	＜10	＜10	＜10	＜10
	Fungus	＜10	＜10	＜10	＜10	＜10	＜10	＜10	＜10

Features

• Safe and gentle.


• No obvious irritation to the skin, no sensitization.


• Can effectively control a variety of bacteria, fungi and yeasts.


• Instead of traditional preservatives, in line with the characteristics of no added preservatives.

Stimulant specification

This product is mild and does not cause significant skin irritation. It is non-toxic and non-sensitizing to the body. Under normal use concentration, there will be slight eye stress irritation.

CAMVA (Chicken Embryo Chorionic Allantoic Membrane Vascularization Test): 0.5%-0.375 (NC value) 1.0%-1.331 (NC value).

Patch test evaluation: 0.5%-6 hrs/12 hrs Negative 1.0%-6 hrs/12 hrs Negative.

Application

Used for all kinds of emulsified cosmetics, including: personal care, maternal and child care, wash care, etc.

Suggested Use

When used alone, the conventional addition amount is 0.8-1.5%, and can be combined with other preservatives after testing.

Notes

1、Avoid adding strong oxidizing substances in the formula, otherwise there is a risk of discoloration.

2、It is recommended to add the water phase before emulsification or after the end of emulsification, and the addition temperature should be less than 80℃. It can also be dissolved in oil phase to make anhydrous formula.

3, in order to ensure its anticorrosive effect, the user must carry out experiments and analysis to determine whether to meet the special requirements of their products, the specific use of the concentration ratio depends on the sensitivity of the customer's products to microbial contamination, hygiene in the production process. Therefore, the actual optimal use of the concentration ratio is determined by the customer through experiments.